Pentosan Polysulfate is a sterile formula that temporarily coats and replenishes the urinary bladder's GAG (glycosaminoglycan) layer. GAGs provide the bladder with a protective layer that works against agents within the urine. This injectable medication is also an effective treatment for osteoarthritis.
What is Pentosan Polysulfate 250 mg/ml, 6 ml?
Pentosan Polysulfate 250 mg/ml, 6 ml is a sterile formulation designed to temporarily coat and replenish the glycosaminoglycan (GAG) layer in the urinary bladder. Injectable Pentosan may be also be useful in treating osteoarthritis in dogs, cats, & horses.
Who is Pentosan Polysulfate 250 mg/ml, 6 ml for?
For use in horses, cats, and dogs.
Why use Pentosan Polysulfate 250 mg/ml, 6 ml?
Pentosan Polysulfate works by coating and replenishing the urinary bladder GAG (glycosaminoglycan) layer. It is a useful treatment for osteoarthritis.
How does Pentosan Polysulfate 250 mg/ml, 6 ml work?
Pentosan Polysulfate, or PPS, is a semi-synthetic polysaccharide ester that is similar to heparin. Derived from the hemicellulose of beechwood, PPS is considered a mild anticoagulant. It has hypolipidemic, fibrinolytic, and anti-inflammatory qualities. PPS is useful in managing and treating osteoarthritis. It is believed to aid in preserving the integrity of cartilage, improving the health of the joints by supporting the anabolic activity of synoviocytes and chondrocytes. It protects against catabolic events in the joints because it reduces cytokine levels and inflammatory mediators in the synovial fluid and cartilage matrix.
250 mg/mL Pentosan Polysulfate Sodium
How is Pentosan Polysulfate 250 mg/ml, 6 ml sold?
Sold as individual 250 mg/ml, 6 ml vial
What are the side effects of Pentosan Polysulfate 250 mg/ml, 6 ml?
Pentosan Polysulfate is shown to be typically well-tolerated. However, the following side effects are possible:
In dogs, mile gastrointestinal effects like:
- Intra-articular bleeding when administered intra-articularly
- Elevated partial thromboplastin time (PTT) for 24 hours or less
What special precautions are there?
- Not approved by the FDA.
- Skin irritation can occur.
- Thoroughly wash hands after handling.
- Wear face protection, eye protection, protective clothing, and protective gloves.
- If skin contact occurs, thoroughly wash with copious amounts of water.
- In case of skin irritation, seek medical attention.
- Contaminated clothing should be removed and washed prior to reuse.
- Keep out of reach of animals and children.
What to do if overdose?
Contact your closest emergency pet hospital.
How can I store Pentosan Polysulfate 250 mg/ml, 6 ml?
Store in a dry and cool environment.
Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.
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